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Type: Pharmaceutical - Pain

A Randomized, Double-Blind, Placebo- Controlled, Multicentre Phase III Study to Evaluate the Efficacy and Safety of Alvimopan 0.5mg Once Daily and 0.5mg Twice Daily for12 weeks for the Treatment of Opioid-Induced Bowel Dysfunction in Adults taking Opioid Therapy for Persistent Non-Cancer Pain.

Year: 2006
Type: Pharmaceutical - Pain
Phase: III
Indication: Pain - General

A Randomized, Double-Blind, Placebo- Controlled, Multicentre Phase III Study to Evaluate the Long-Term Safety of Alvimopan 0.5mg Twice Daily for 12 Months for the Treatment of Opioid-Induced Bowel Dysfunction in Adults taking Opioid Therapy for Persistent Non-Cancer Pain.

Year: 2007
Type: Pharmaceutical - Pain
Phase: III
Indication: Pain - General

A Randomised Double-Blind, Placebo-and-Active-Control, Parallel-arm, Phase III Trial with Controlled Adjustment of Dose to Evaluate the Efficacy and Safety of CG5503 Extended –Release (ER) in Subjects with Moderate to Severe Chronic Low Back Pain.

Year: 2008
Type: Pharmaceutical - Pain
Phase: III
Indication: Back and/or Leg Pain

A Double-Blind Placebo-Controlled study of the efficacy and safety of the p38 Map kinase inhibitor SB681323 in patients with neuropathic pain following nerve trauma.

Year: 2009
Type: Pharmaceutical - Pain
Phase: II
Indication: Neuropathic Pain

A randomised, double-blind, placebo-controlled study of the efficacy and safety of a diclofenac sodium patch for the topical treatment of acute pain due to mild to moderate soft tissue injuries.

Year: 2009
Type: Pharmaceutical - Pain
Phase: III
Indication: Pain - General

A Multicentre, Randomised, Double-Blind, Parallel Group Comparison of The Efficacy and Safety of Transdermal Buprenorphine (Norspan® TDS) And Placebo in Participants with Post Herpetic Neuralgia.

Year: 2010
Type: Pharmaceutical - Pain
Phase: III, IV
Indication: Postherpetic Neuralgia

Open-label study to evaluate the Long-Term Safety of Subcutaneous MOA-728 for Treatment of Opioid-Induced Constipation in Subjects with Non-malignant Pain.

Year: 2010
Type: Pharmaceutical - Pain
Phase: III
Indication: Pain - General

A confirmatory, placebo-controlled, randomised, double-blind, single dummy, parallel group, ratio-finding study in constipated pain patients to establish an optimal Hydromorphone – naloxone ratio with an improved bowel function and a comparable analgesic efficacy compared to Hydromorphone alone.

Year: 2011
Type: Pharmaceutical - Pain
Phase: II, III
Indication: Pain - General

Efficacy and safety of Transdermal Buprenorphine (Norspan BTDS) and placebo in patients with Diabetic Peripheral Neuropathic Pain (DPNP).

Year: 2011
Type: Pharmaceutical - Pain
Phase: IIIb
Indication: Painful Diabetic Neuropathy

Use of Duloxetine or Pregabalin in Monotherapy versus Combination Therapy of Both Drugs in Patients with Painful Diabetic Neuropathy “The COMBO – DN” (Combination vs Monotherapy of Pregabalin and duloxetine in Diabetic Neuropathy).

Year: 2012
Type: Pharmaceutical - Pain
Phase: IIIb
Indication: Painful Diabetic Neuropathy

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