A First-in-Human Open-Label Phase 1/2a Study to Evaluate Safety, Tolerability and Efficacy of a Single Intra-Articular Injection of Allogeneic Mesenchymal Stem Cells Selected for Integrin α10β1 (XSTEM-OA) in Adult Patients with Symptomatic Knee Osteoarthritis.
Year: 2023
Type: Musculoskeletal
Phase: First-in-Human, I, IIa
Indication: Knee Osteoarthritis
A Multiple Arm, Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm, Phase 2 Study of Intra-Articular Administration of an Allogeneic Human Placental Tissue Particulate (PTP-001) for the Treatment of Knee Osteoarthritis.
Year: 2022
Type: Musculoskeletal
Phase: II
Indication: Knee Osteoarthritis
A 5-year, Randomized, Double-blind, Placebo-controlled, Multi-center Study Assessing the Efficacy, Safety, and Tolerability of Intra-articular Regimens of LNA043 Versus Placebo in Patients With Symptomatic Knee Osteoarthritis (ONWARDS).
Year: 2021
Type: Musculoskeletal
Phase: IIb
Indication: Knee Osteoarthritis
A Study to Compare the Preference for Two Contrasting Paracetamol Formulations In The Management of Osteoarthritis Pain.
Year: 2008
Type: Musculoskeletal
Phase: IV
Indication: Knee Osteoarthritis
A Randomised Double-Blind, Placebo-and-Active-Control, Parallel-arm, Phase III Trial with Controlled Adjustment of Dose to Evaluate the Efficacy and Safety of CG5503 Extended –Release (ER) in Subjects with Moderate to Severe Pain Due to Osteoarthritis of the Knee.
Year: 2008
Type: Musculoskeletal
Phase: III
Indication: Knee Osteoarthritis
A Double Blind, Randomised, Parallel Group, Dose-Ranging Study Comparing FX006 to Commercially Available Triamcinolone Acetonide Injectable Suspension in Patients with Osteoarthritis of the Knee.
Year: 2012
Type: Musculoskeletal
Phase: II
Indication: Knee Osteoarthritis
A Multi centre, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Hydros and Hydros-TA Joint Therapies for Management of Pain Associated with Osteoarthritis in the Knee.
Year: 2015
Type: Musculoskeletal
Phase: III
Indication: Knee Osteoarthritis
A Double-Blind, Randomized, Single-Dose Study to Assess the Safety and Efficacy of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee.
Year: 2016
Type: Musculoskeletal
Phase: III
Indication: Knee Osteoarthritis
A Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of AXS-02 (Disodium Zoledronate Tetrahydrate) Administered Orally to Subjects with Knee Osteoarthritis Associated with Bone Marrow Lesions.
Year: 2016
Type: Musculoskeletal
Phase: IIa
Indication: Knee Osteoarthritis
A randomised, double-blind using blinded evaluator, placebo and active controlled, pilot study to evaluate the safety and efficacy of intra articular administration of Articul One in patient with symptomatic primary knee osteoarthritis.
