Indication: Painful Diabetic Neuropathy

Single-Arm, Multicenter, Study to Evaluate Safety and Efficacy of Ultra-Low Frequency Spinal Cord Stimulator in Subjects with Painful Diabetic Neuropathy.
Efficacy and safety of Transdermal Buprenorphine (Norspan BTDS) and placebo in patients with Diabetic Peripheral Neuropathic Pain (DPNP).
Use of Duloxetine or Pregabalin in Monotherapy versus Combination Therapy of Both Drugs in Patients with Painful Diabetic Neuropathy “The COMBO – DN” (Combination vs Monotherapy of Pregabalin and duloxetine in Diabetic Neuropathy).
A double-blind, placebo-controlled, randomized trial to determine the safety and efficacy of EMA401 100 mg b.i.d. in reducing 24-hour average pain intensity score in patients with painful diabetic neuropathy (EMPADINE).